POLICOSANOL 20MG 60CAPS POLICOSANOL LIKE POLINOL

Policosanol. 20mg. 60 capsules. Swanson
More potent than Polinol

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Policosanol is a chemical obtained from sugar cane and other sources. ... Policosanol is used for conditions that affect the health of the heart and blood vessels including high cholesterol, leg pain due to poor circulation (intermittent claudication), and narrowing of the blood vessels that serve the heart. P
• An all-natural substance promoting healthy lipid levels • A perfect complement to daily exercise and a healthy diet for cardiovascular system support • Extracted from the waxy part of all-natural sugar cane Dont take your heart health for granted -- take control of your cardiovascular care with Swanson Ultra Policosanol. Derived from an all-natural sugarcane base, our BioCosanol policosanol is recognized as the worlds finest policosanol source, featuring the ideal ratios of octacosanol, triacontanol and hexacosanol for promoting heart-healthy lipid levels in the bloodstream. Available exclusively from Swanson Ultra, it makes a great addition to a healthy diet and exercise program for everyday cardiovascular care. Supplement Facts Amount Per Capsule Policosanol (from BioCosanol) 20 mg Typical Aliphatic Alcohol Profile: Octacosanol 10–12 mg Triacontanol 3–6 mg Hexacosanol 1–4 mg Suggested Use: As a dietary supplement, take one capsule one to two times per day with water.
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Effects of policosanol 20 versus 40 mg/day in the treatment of patients with type II hypercholesterolemia: a 6-month double-blind study.
Castaño G1, Mas R, Fernández L, Illnait J, Gámez R, Alvarez E.
Author information
Abstract
Policosanol is a well defined mixture of higher aliphatic primary alcohols isolated from sugar cane wax with cholesterol-lowering effects proven for a dose range from 5-20 mg/day in patients with type II hypercholesterolemia and dyslipidemia associated with noninsulin dependent diabetes mellitus. This randomized, double-blind study investigated the cholesterol-lowering efficacy and tolerability of policosanol 20 mg/day compared with 40 mg/day. Changes in low-density lipoprotein (LDL)-cholesterol levels were predefined as the primary efficacy endpoint. Patients with type II hypercholesterolemia were enrolled in the study and instructed to continue a step I cholesterol-lowering diet for 6 weeks and those eligible to be included (89) were randomly allocated to receive under double-blind conditions placebo (n = 30), policosanol 20 mg/day (n = 29) or 40 mg/day (n = 30). After 24 weeks, policosanol at 20 and 40 mg/day significantly (p

All the above-mentioned significant differences were also different from placebo and no significant changes occurred in any lipid profile parameters in the placebo group. Based on the mean values of LDL-cholesterol levels at study completion, the mean percent reductions from baseline were 27.4% and 28.1% for the 20 and 40 mg/day groups, respectively. Thus, the effects of both policosanol doses on the main efficacy variable were practically identical. Consistent with the data obtained for LDL-cholesterol, both doses were similarly effective in changing all the other lipid profile parameters. No unexpected adverse effects were observed and there were no significant between-group differences regarding safety indicator values or reported adverse effects. In conclusion, although the tolerability profile remains excellent, according to the present results policosanol at a dose of 40 mg/day does not offer significant additional cholesterol-lowering efficacy over the 20 mg/day dose.
PMID: 11708574
[Indexed for MEDLINE]
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1521 Nov